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BP神经网络 2

加速遗传算法 2

智能制造 2

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Trajectory planning and base attitude restoration of dual-arm free-floating space robot by enhanced bidirectionalapproach

Zongwu XIE1 , Xiaoyu ZHAO1 , Zainan JIANG1 , Haitao YANG2 , Chongyang LI1

《机械工程前沿（英文）》 2022年第17卷第1期 doi: 10.1007/s11465-021-0658-y

摘要： When free-floating space robots perform space tasks, the satellite base attitude is disturbed by the dynamic coupling. The disturbance of the base orientation may affect the communication between the space robot and the control center on earth. In this paper, the enhanced bidirectional approach is proposed to plan the manipulator trajectory and eliminate the final base attitude variation. A novel acceleration level state equation for the nonholonomic problem is proposed, and a new intermediate variable-based Lyapunov function is derived and solved for smooth joint trajectory and restorable base trajectories. In the method, the state equation is first proposed for dual-arm robots with and without end constraints, and the system stability is analyzed to obtain the system input. The input modification further increases the system stability and simplifies the calculation complexity. Simulations are carried out in the end, and the proposed method is validated in minimizing final base attitude change and trajectory smoothness. Moreover, the minute internal force during the coordinated operation and the considerable computing efficiency increases the feasibility of the method during space tasks.

关键词： free-floating space robot dual arm coordinated operation base attitude restoration bidirectional approach

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Development of a masticatory robot using a novel cable-driven linear actuator with bidirectional motion

《机械工程前沿（英文）》 2022年第17卷第4期 doi: 10.1007/s11465-022-0687-1

摘要： Masticatory robots are an effective in vitro performance testing device for dental material and mandibular prostheses. A cable-driven linear actuator (CDLA) capable of bidirectional motion is proposed in this study to design a masticatory robot that can achieve increasingly human-like chewing motion. The CDLA presents remarkable advantages, such as lightweight and high stiffness structure, in using cable amplification and pulley systems. This work also exploits the proposed CDLA and designs a masticatory robot called Southeast University masticatory robot (SMAR) to solve existing problems, such as bulky driving linkage and position change of the muscle’s origin. Stiffness analysis and performance experiment validate the CDLA’s efficiency, with its stiffness reaching 1379.6 N/mm (number of cable parts n = 4), which is 21.4 times the input wire stiffness. Accordingly, the CDLA’s force transmission efficiencies in two directions are 84.5% and 85.9%. Chewing experiments are carried out on the developed masticatory robot to verify whether the CDLA can help SMAR achieve a natural human-like chewing motion and sufficient chewing forces for potential applications in performance tests of dental materials or prostheses.

关键词： masticatory robot cable-driven linear actuator parallel robot stiffness analysis

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Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition

null

《医学前沿（英文）》 2016年第10卷第3期页码 311-319 doi: 10.1007/s11684-016-0460-0

摘要：

We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e., Tac-β3, Tac-β3D741, Tac-β3D747, Tac-β3D754, Tac-β3D759, and Tac-β3DNITY) consisting of the extracellular and transmembrane domains of human IL-2 receptor (Tac) and the human integrin β3 cytoplasmic domain were stably expressed in the 123 CHO cells harboring human glycoprotein Ib-IX and wild-type integrin αIIbβ3. The different cells were assayed for stable adhesion and spreading on immobilized fibrinogen, and for binding soluble fibrinogen representing outside-in and inside-out signaling events, respectively. The chimeric protein Tac-β3 inhibited, and Tac-β3DNITY partially attenuated stable adhesion and spreading. Tac-β3, Tac-β3D759, Tac-β3DNITY, and Tac-β3D754, but not Tac-β3D747 or Tac-β3D741, impaired the soluble fibrinogen binding. Results indicated that the bidirectional signaling was significantly inhibited by Tac-β3 and Tac-β3DNITY, albeit to a much lesser extent. Moreover, only inside-out signaling was impaired in the 123/Tac-β3D759 and 123/Tac-β3D754 cells in contrast to an intact bidirectional signaling in the 123/Tac-β3D747 and 123/Tac-β3D741 cells. In conclusion, the calpain cleavage of integrin β3 resulted in the regulatory effects on signaling by interrupting its interaction with cytoplasmic proteins rather than altering its conformation, and may thus regulate platelet function.

关键词： integrin β3 signal transduction trans-dominant inhibition model

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脉冲型惯性双向联想记忆神经网络新解 Research Articles

Chaouki AOUITI, Mahjouba Ben REZEG, Yang CAO

《信息与电子工程前沿（英文）》 2020年第21卷第2期页码 324-339 doi: 10.1631/FITEE.1900181

摘要：探究了具有混合时滞和脉冲效应的惯性双向联想记忆神经网络。该研究为类似系统的反周期解的存在性、唯一性和全局指数稳定性提供了新的实用条件。使用微分不等式技术证明我们的主要结果，并给出一个仿真算例证明新结果的有效性。

关键词：惯性神经网络；反周期解；全局指数稳定；脉冲；时变延迟；双向联想记忆

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联网型直流微电网并联双向变流器分层控制 Article

Hui-yong HU, Yong-gang PENG, Yang-hong XIA, Xiao-ming WANG, Wei WEI, Miao YU

《信息与电子工程前沿（英文）》 2017年第18卷第12期页码 2046-2057 doi: 10.1631/FITEE.1601497

摘要：直流微电网通过多个双向变流器并联连接到交流电网，其控制方法直接影响到直流电网的性能。目前的研究工作主要集中在交流、直流及混合微电网的分层控制，而较少关注直流微电网互联的双向变流器的分层控制。本文提出一种直流微电网联网双向变流器的分层控制方法。为抑制交流测零序环流并实现电压控制的反馈线性化，采用d-q-0控制策略来控制内环电流并采用直流电压平方实现外环电压控制。在一次控制阶段采用直流电压下垂控制来实现直流电流的分担，直流电压下垂控制会产生直流电压偏差。接着分析了直流电压偏差和电流分担误差之间的关系。为同时消除直流电压偏差和电流分担误差，在二次控制中采用了下垂斜率调节和电压平移。三次控制中通过多双向变流器的精确有功和无功控制实现直流微网的经济运行。本文提出的直流微网多并联双向变流器分层控制方法可以实现微网内可控/不可控分布式电源的协调。通过Matlab/Simulink仿真验证了算法的有效性，结果表明该算法能满足实际应用需求。

关键词：并联双向变流器；分层控制；直流微电网

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TRANSLATING THE MULTI-ACTOR APPROACH TO RESEARCH INTO PRACTICE USING A WORKSHOP APPROACH FOCUSING ON

《农业科学与工程前沿（英文）》 2021年第8卷第3期页码 460-473 doi: 10.15302/J-FASE-2021416

摘要：

The EIP-Agri multiactor approach was exemplified during a 3-day workshop with 63 project participants from the EU H2020 funded project “Redesigning European cropping systems based on species MIXtures”. The objective was to share firsthand experience of participatory research among researchers who were mostly not familiar with this approach. Workshop participants were divided into smaller multidisciplinary groups and given the opportunity to interact with representatives from eight actor positions in the value chain of the agrifood cooperative Terrena located in Western France. The four stages of the workshop were: (1) key actor interviews, (2) sharing proposed solutions for overcoming barriers, and (3) developing possible interdisciplinary concepts. Expressions of frustration were recorded serving both as a motivation for group members to become more aware of the scientific concerns and practices of their colleagues, as well as a recognition that some researchers have better skills integrating qualitative approaches than others. Nevertheless, the workshop format was an effective way to gain a common understanding of the pertinent issues that need to be addressed to meet overall multiactor-approach objectives. Working with the actor networks was identified and emphasized as a means to overcome existing barriers between academia and practice in order to coproduce a shared vision of the benefits of species mixture benefits.

关键词： agroecology codesign intercropping knowledge sharing participatory methods

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免疫球蛋白G N-糖基化与代谢特征之间的双向因果关联——一项孟德尔随机化研究 Article

孟晓妮, 曹维杰, 刘迪, Isinta Elijah Maranga, 邢薇佳, 侯海峰, 徐希柱, 宋曼殳, 王友信

《工程（英文）》 2023年第26卷第7期页码 74-88 doi: 10.1016/j.eng.2022.11.004

摘要：

既往研究已发现免疫球蛋白 G（immunoglobulin G, IgG）N-糖基化与代谢特征之间存在关联，但它们之间是否存在因果关联尚有待研究。本研究使用孟德尔随机化（Mendelian randomization, MR）研究方法整合全基因组关联研究（genome-wide association studies, GWAS）和数量性状基因座（quantitative trait loci, QTL）数据探究IgG N-糖基化与代谢特征之间的双向因果关联。在正向MR分析中，通过整合IgG N-糖基-QTL遗传变异与GWAS 数据和代谢特征进行分析，分别发现59个包括影响体质指数（body mass index, BMI）的9个IgG N-糖基（glycan peaks, GP）（GP1和GP6等）和影响空腹血糖（fasting plasma glucose, FPG）的 7个IgG N-糖基（GP1和GP5等）以及15个[包括影响BMI 的5个IgG N-糖基（GP2 和 GP11 等）和影响FPG的 4个IgG N-糖基（GP1和GP10等）]由遗传决定的 IgG N-糖基在单样本和两样本MR研究中与代谢特征存在因果关联（全部 P < 0.05）。相应地，对整合代谢特征-QTL-遗传变异与GWAS结果和 IgG N-糖基进行MR分析的结果显示，在单样本和两样本MR研究中，分别发现72个包括影响GP1的1个因果代谢特征[高密度脂蛋白胆固醇（high-density lipoprotein cholesterol, HDL-C）]和影响GP2的5个因果代谢特征[FPG、收缩压（systolic blood pressure, SBP）等]和4个[包括影响GP3的1个因果代谢特征（HDL-C）和影响 GP9 的1个代谢特征（HDL-C）]由遗传决定的代谢特征与 IgG N-糖基之间存在因果关联（全部 P < 0.05）。值得注意的是，在单样本和两样本的MR分析中均发现了遗传决定的高水平的GP11与BMI水平增高存在因果关联[固定效应模型-Beta (SE): 0.106 (0.034) 和 0.010 (0.005)]和高水平的HDL-C与 GP9 水平降低存在因果关联[−0.071 (0.022) 和−0.306 (0.151)]，且这一结果在单样本和两样本的 meta汇总分析中得到了进一步验证[固定效应模型-Beta（95%置信区间）分别为：0.0109 (0.0012, 0.0207) 和−0.0759 (−0.1186, −0.0332)]。综上所述，本研究全面的双向MR分析提供了IgG N-糖基化与代谢特征之间双向因果关联的证据，在一定程度上揭示了 IgG N-糖基化与代谢特征之间的生物学机制。

关键词：孟德尔随机化研究免疫球蛋白 G N-糖基化代谢特征数量性状位点双向因果关联

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深度IA双向智能 Personal View

Lei XU

《信息与电子工程前沿（英文）》 2020年第21卷第4期页码 558-562 doi: 10.1631/FITEE.1900541

摘要：概述了一个深度双向智能框架。由底向上方向有两个行为，一是获取信息形成适当的模式表示，二是抽象—自组织认知，简记为“A-S认知”，将输入模式抽象为概念，由一个标签表示，并通过自组织学习以理解模式构成的层次表示。而顶层内域中的行为统称为“A-I思维”，包含积累、融合、归纳、和灵感等。由顶向下方向也有两个行为，一个简称“I-S推理”，进行推理和综合，执行各种形象思维和问题求解任务，另一个是与环境交互，执行控制、通讯和检验的任务。在这个双向智能框架基础上，探讨了进行综合推理的可能性。

关键词：抽象；最小均方误差重建自组织学习（Lmser）；认知；形象思维；抽象思维；综合推理

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Governance approach to China’s environmental challenges: Towards a theoretical synthesis

QI Ye, XUE Lan, ZHANG Lingyun

《环境科学与工程前沿（英文）》 2007年第1卷第4期页码 385-400 doi: 10.1007/s11783-007-0066-5

摘要： This paper reviewed recent research in environmental governance as a response to environmental challenges at various spatial, temporal and administrative scales. It documented the shift of approach from regulation to governance, and attempted to provide a comprehensive understanding why and how the transformation occurred. It also described major factors and forces of environmental governance, and discussed research advance in environmental governance theory. Finally, this paper summarized recent research findings on environmental governance in China, and listed policy recommendation for enhancing the governance.

关键词： environmental governance approach temporal regulation various

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Comparison of surgical indications for hysterectomy by age and approach in 4653 Chinese women

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《医学前沿（英文）》 2014年第8卷第4期页码 464-470 doi: 10.1007/s11684-014-0338-y

摘要：

Approximately one million hysterectomies are performed each year in China. However, national data regarding the indications and the surgical approaches for hysterectomy are lacking. The aim of this study was to examine the surgical indications for hysterectomy in different age groups and the relative merits of different surgical approaches for hysterectomy in Chinese women. Clinical data from 4653 cases of hysterectomy performed in Tongji Hospital from 2004 to 2009 were analysed. Hysterectomy was most commonly performed among women aged 40--49 years (2299; 49.4%). Overall, colporrhagia and abdominal pain were the two most common indications for hysterectomy. The most common indications by age groups were as follows: malignant ovarian tumour,<20 years; malignant uterine tumour, 20--29 and 30--39 years; uterine myoma, 40--49 and 50--59 years; and uterine prolapse, 60--69 and>70 years. The proportion of malignant aetiology also varied by age, being the highest in women aged<20 years (75.0%) and the lowest in those aged 40--49 years (19.9%). Approximately 35% women who had hysterectomies also had concomitant bilateral oophorectomy. The lowest rate of oophorectomy occurred in women aged 30--39 years (15.8%), whereas the highest rate was in those aged 50--59 years (75.9%). The abdominal surgical approach was used in 84% of all hysterectomies. Surgeries using the vaginal approach required a significantly shorter operating time (118 min average) than all other approaches (P<0.05). Both the amount of bleeding and the blood transfusion volume required were smaller in vaginal approaches, with no significant differences between the others. The surgical approaches used were also related to the scope of surgery. Both the surgical indications and the rates of bilateral oophorectomy varied by age. In terms of both operating time and the amount of bleeding and blood transfusion volume required, the vaginal approach was superior to all other surgical approaches.

关键词： hysterectomy surgical indications surgical approach bilateral oophorectomy

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Hierarchical approach for fatigue cracking performance evaluation in asphalt pavements

Ibrahim ONIFADE, Yared DINEGDAE, Björn BIRGISSON

《结构与土木工程前沿（英文）》 2017年第11卷第3期页码 257-269 doi: 10.1007/s11709-017-0410-1

摘要： In this paper, a hierarchical approach is proposed for the evaluation of fatigue cracking in asphalt concrete pavements considering three different levels of complexities in the representation of the material behaviour, design parameters characterization and the determination of the pavement response as well as damage computation. Based on the developed hierarchical approach, three damage computation levels are identified and proposed. The levels of fatigue damage analysis provides pavement engineers a variety of tools that can be used for pavement analysis depending on the availability of data, required level of prediction accuracy and computational power at their disposal. The hierarchical approach also provides a systematic approach for the understanding of the fundamental mechanisms of pavement deterioration, the elimination of the empiricism associated with pavement design today and the transition towards the use of sound principles of mechanics in pavement analysis and design.

关键词： fatigue cracking energy based crack initiation mechanistic approach pavement analysis

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Critical flow-storm approach to total maximum daily load (TMDL) development: an analytical conceptual

Zhang Harry, Yu Shaw

《环境科学与工程前沿（英文）》 2008年第2卷第3期页码 267-273 doi: 10.1007/s11783-008-0058-0

摘要： One of the key challenges in the total maximum daily load (TMDL) development process is how to define the critical condition for a receiving waterbody. The main concern in using a continuous simulation approach is the absence of any guarantee that the most critical condition will be captured during the selected representative hydrologic period, given the scarcity of long-term continuous data. The objectives of this paper are to clearly address the critical condition in the TMDL development process and to compare continuous and event-based approaches in defining critical condition during TMDL development for a waterbody impacted by both point and nonpoint source pollution. A practical, event-based critical flow-storm (CFS) approach was developed to explicitly addresses the critical condition as a combination of a low stream flow and a storm event of a selected magnitude, both having certain frequencies of occurrence. This paper illustrated the CFS concept and provided its theoretical basis using a derived analytical conceptual model. The CFS approach clearly defined a critical condition, obtained reasonable results and could be considered as an alternative method in TMDL development.

关键词： representative hydrologic occurrence simulation approach scarcity alternative